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For example, the cost could be defined as the random time taken by each trial in an experiment, and one might wish to maximize the expected total information gain over as many trials as can be completed in 15 min.
More than half of these trials originated in India; more than twice as many trials as had then been conducted in the USA [ 9].
The task was self-paced and they were instructed to accomplish as many trials as they could in 45 s.
Each training session included as many trials as a rat would perform before quitting, approximately 150 250.
One prisoner, Gary Nelson, described at one of his many trials as one of "the most violent and dangerous men to walk the streets of Britain", is believed to hold the dubious record for being the country's most ghosted prisoner, having been moved to 33 jails in four years.
Gary Nelson, described at one of his many trials as one of "the most violent and dangerous men to walk the streets of Britain", is believed to hold the dubious record for being the country's most ghosted prisoner, having been moved to 33 jails over just one four-year period.
Similar(43)
Thiazides have been shown to lower blood pressure in many trials, but as far as we are aware nobody has asked or tested whether they have an effect on BP variability.
This is sufficient for many behavioural trials as well as drug trials where immediate randomisation is required.
Many trials take twice as long to enroll as planned, which contributes to the unsustainable costs of over $2 billion for developing each new medicine.
No matter how many trials prove duds, as long the drug maker can produce two trials that show some clinically significant difference between the drug and the placebo, it generally gets the drug approved.
Limits include a small sample size in many of the trials as well as questionable randomization and at least investigator-blinding methods.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com