Here we have identified many transcripts coding for this enzyme.
Many transcripts coding for UDP-glucosyl transferases have been identified in this study.
Analysis of the sialotranscriptome of two R. sanguineus cDNA libraries, from RsSGL1 and RsSGL2, identified many transcripts coding for different components that can favor the tick in detriment of the host.
Many transcripts coding for the protein synthesis machinery, protein transport and processing, energy metabolism, lipid metabolism, membrane-associated proteins and molecular transporters were also strongly altered in the P25-expressing plants.
Importantly, iron is a required cofactor for many of the transcripts coding for enzymes associated with ergosterol biosynthesis steps that were increased in response to hypoxia (erg25 and erg11).
Many of these transcripts coding for proteases (peptidase C1, peptidase S1, peptidase S6, TRY2, TRY3, TRY4, TRY5, TRY6, TRY7, several serine proteases, carboxypeptidases, and aminopeptidases) and glycosidases (four maltase transcripts AGAP011939-RA, AGAP012401-RA, AGAP002102-RA, and AGAP008965-RA and a chitinase transcript AGAP008061-RA) have a secretory signal peptide sequence.
Many of the transcripts coding for putative Glycera toxins belong to classes that have been widely recruited into venoms, but some are homologs of toxins previously only known from the venoms of scorpaeniform fish and monotremes (stonustoxin-like toxin), turrid gastropods (turripeptide-like peptides), and sea anemones (gigantoxin I-like neurotoxin).
Many of the differentially regulated biotransformation transcripts coded for the same Genbank accession.
Many transcripts were also found coding for various water channels of the aquaporin family and the alpha-1 subunit of the Ca++ channel, the voltage gated Ca++ channel, the rectifier potassium channel, the tandem pore K+ channel, Cl- and ligand gated ion channels.
Of the 726 candidate retrocopies whose expression was supported by many transcripts, 624 were composed of single protein coding exons and 102 contained multiple protein coding exons.
However, polycistronic transcripts do not all code for putative uORFs; many transcripts defined as polycistronic are initially transcribed as pre-mRNA with two or more ORFs, but are subsequently processed into separate monocistronic transcripts [ 25].
