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Terminal differentiation occurs not only in embryonic development but also in many tissues in postnatal life.
The bone of skeletons is one of many tissues in our bodies, made like the rest from instructions in our DNA.
Moreover, NAG is found in many tissues in the body and has been reported previously to be detectable in serum [27].
Among the novel AAV serotypes cloned and engineered for production of recombinant vectors, AAV8 has shown a tremendous potential for in vivo gene delivery with nearly complete transduction of many tissues in rodents after intravascular infusion.
Of course, researchers don't know whether such a drug would have other side effects, because the IL-15Rα gene is expressed in many tissues in the body, not just muscles.
Transcription factors of the bHLH family are well-characterized regulators of differentiation processes in many tissues in vertebrates.
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Bacterial endotoxins and proinflammatory cytokines up-regulate ADM gene expression in many tissues, both in vitro and in vivo in rodents and humans [ 38, 39].
Bacterial endotoxins and proinflammatory cytokines upregulate ADM gene expression in many tissues, both in vitro and in vivo in rodents and humans [ 5, 26].
In many tissues, and in skeletal muscle in particular, the number and size of mitochondria vary strongly (1-25 μm) depending on the type of skeletal muscle.
Second, evidence is accumulating that fusion may occur in vivo in many tissues, resulting in cell reprogramming and thus contributing to regeneration (Sanges et al, 2011).
The α form is present in many tissues, especially in the liver, β predominates in muscle and γ is only found in brain cells.
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