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But, unlike granulocytes, monocytes undergo differentiation, becoming macrophages that settle in many tissues, especially the lymphoid tissues (e.g., spleen and lymph nodes) and the liver, which serve as filters for trapping microbes and other foreign particles that arrive through the blood or the lymph.
Application of the traditional method of direct in vivo RBC labeling resulted in the calculation of negative interstitial volume values for many tissues, especially clearance organs (data not shown).
In human CMBL was widely expressed in many tissues, especially in liver and intestine [ 41].
Haem is synthesised in many tissues, especially liver and erythroid cells [ 255].
However, oxygen and nutrient supply are limiting factors in many tissues, especially after implantation into the host.
DOI: http://dx.doi.org/10.7554/eLife.03941.001 Dystroglycan is a protein that is critical for the proper function of many tissues, especially muscles and brain.
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These data indicated that TLR4 was required for basal radio-resistance by suppression of apoptosis in many tissues, and especially the BMC.
Estrogenic compounds may influence the growth, differentiation and function in many target tissues, especially in the female reproductive tract during pregnancy.
Although every attempt was made to amplify sequences from identical tissues from all patients, this was impossible due to several factors, including the fact that many brain tissues, especially from those patients without extensive brain disease, contained no amplifiable HIV.
IGFBP4 is produced mainly in the liver but many other tissues, especially neoplastic tissue, produce it (Korc-Grodzicki et al, 1993; Lewinski et al, 2004).
22, 23 It has also been reported that EpCAM is an early biomarker commonly overexpressed in many premalignant tissues, especially in epithelial neoplasia.
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