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However, thyroxine is converted to triiodothyronine in many tissues by the action of enzymes called deiodinases.
Complement proteins are produced by liver cells and, in many tissues, by macrophages.
MiRNAs are small, non-coding transcripts that functioned in many tissues by repressing target gene expression (Chen et al., 2012).
It is involved in receptor tyrosine kinase signaling in many tissues by generating signaling complexes in response to receptor activation [8], [9].
Outside of the CNS, GFAP is expressed widely in many tissues by a variety of cell types, also discussed below.
The subcellular localisations of the CPTI lines have been characterised in many tissues by a consortium of UK groups and the information is centralized in the Flyprot website, www.flyprot.org (Lowe et al., 2014).
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Insulin-like growth factor 1 (IGF-1) is produced by many tissues, mainly by the liver, and it is involved in biologic processes such as osteoblasts growth and differentiation [ 19].
Second, many tissues injured by ischemia, mechanical trauma, excitotoxins, and other stressors are significantly improved by administration of rhEPO following injury (reviewed by Erbayraktar and coworkers [ 25] and by Beumi and coworkers [ 26]) in multiple species, including humans [ 27].
Cell divisions and therefore replication errors occur in many tissues, and by analogy to species molecular clocks, a reliable somatic cell molecular clock should allow comparisons among tissues.
Photodynamic therapy (PDT) is a promising technique for the treatment of small tumours in organs where it is essential to minimise damage to immediately adjacent normal tissue as PDT damage to many tissues heals by regeneration rather than scarring.
Further, this study is important in demonstrating that the alterations in morphology and physiology induced in free-ranging individuals living in environments contaminated with endocrine-active compounds are not limited to a few systems or tissues; rather, effects can be observed in many tissues affected by these hormones.
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