Sentence examples for many tissues as from inspiring English sources

Wnt signaling cascades play a crucial role in the maintenance of stem cell niches in many tissues as well as in embryonic patterning and cell-fate determination.

Altogether, this method will likely be particularly useful for genes with multiple separate functions, genes expressed in many tissues, as well as in cases where altered gene expression causes embryonic lethality.

It has become apparent that human obesity is associated with activation of the ECS and with increased levels of ECs in many tissues, as well as in the circulation [17] However, the underlying molecular mechanisms of ECS dysregulation in obesity need clarification to better understand ECS risk factors in obesity and to develop novel selective treatment strategies.

Some of the MRX genes are ubiquitously expressed and mutations within these genes cause cellular defects in many tissues, as well as predominantly affecting the brain because of its higher sensitivity [ 5].

The set of significantly altered miRNAs exhibited a wide variety of expression levels and synaptic enrichment ratios; they comprised miRNAs expressed widely in many tissues as well as miRNAs that are primarily expressed in brain and in neurons (results not shown).

An attempt was made to include as many tissues as possible, even though some tissues had only a few expression profiles available in the GEO database.

For example, a mitosis related kinase gene VRK1 was found to be active in many hematological tissues as well as in the many tumors of connective and muscular tissues (sarcomas, head & neck and melanoma) and in most gynecological cancers (uterine, ovarian and breast cancers) (Figure 6A B).

TRP channels are distributed in many peripheral tissues as well as central and peripheral nervous system.

However, this pathway is ubiquitous not only in malignant, but in many healthy tissues as well.

Anterior gradient 2 (AGR2) is a protein disulfide isomerase-like protein widely expressed in many normal tissues as well as cancers.

In addition to efficacy in the liver, antagomirs have now shown pharmacological activity in many other tissues as well (reviewed in: Thum, 2012).