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Methods for high throughput screening against these targets are generally limited to in vitro biochemical assays that can suffer many technical limitations, as well as failing to capture the biological context of proteases within the cellular pathways that lead to their activation.
However, conventional transvaginal mesh excision has many technical limitations.
There are many technical limitations in enabling safe MR scanning of CIEDs.
Considering the many technical limitations facing the selective blocking of sites, as well as the danger posed to civil liberties by regulatory overreach, it would seem natural for the government to focus its resources on the more pressing concern of child pornography rather than pursue the quixotic task of imposing an all-encompassing porn prohibition.
Besides the possibility to perform single cell BRET assays [ 190], there are many technical limitations because of the reduced intensity of light released when luciferase oxidizes its substrate.
However, acquiring direct evidence for the exchange of active biomolecules between tumor cells in vivo so far remained challenging due to many technical limitations (Raposo and Stoorvogel, 2013; Théry, 2011).
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Many of the technical limitations in traditional adaptive control, such as matching condition and relative-degree constraint, can be eliminated by an adaptive backstepping control scheme.
Drilled-and-grouted (D&G) piles overcome many of the technical limitations associated with impact piling in carbonate deposits, however D&G piles are both expensive and time consuming to construct.
While distributed conferencing service architecture can overcome many of the technical limitations of centralized architecture, the business model of the distributed conferencing architecture can create a win-win service for participants in which they can contribute their computation and get a free service in return (or they can even contribute their computation for their direct financial gain).
As many participants as technical limitations permitted (i.e., materials and costs) were included for sampling.
The second generation OCT imaging system may eliminate many of the technical limitations of the present study.
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many technical innovations
many technical devices
many technical analysts
many inherent limitations
many technical yarns
many technical modifications
many technical issues
many technical factors
many technical problems
many technical appendices
many technical difficulties
many technical processes
many technical things
many technical countermeasures
many technical books
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