Sentence examples for many targets that from inspiring English sources

Although the filtered families consist of compounds that have significant experimental activities against the relevant targets, there are many targets that have distinct groups of ligands with different scaffolds.

"There were many targets that were media outlets," she told HuffPost Live.

These studies confirmed that the constitutive mRNA expression of many targets that were regulated by P53 in melanocytes were unaffected in melanoma, suggesting that P53 had lost the ability to regulate the expression of these transcripts in melanoma.

We believe microarray is still useful for accurate gene expression analysis at high throughput level [ 33], however, it is relative low sensitive for detection of rare transcripts and potentially can miss many targets that is not included on the array [ 34].

A single miRNA might have many targets that are involved in different oncogenic pathways, and a small group of miRNAs are consistently deregulated in a wide variety of hematological malignancies and solid tumors; developing strategies to silence or reexpress these miRNAs will likely affect several groups of patients [ 47].

Some examples of proteins that are in the H-List include known targets such as InhA, EmbA and FabH, as well as many targets that have been proposed for anti-tubercular drug discovery, such as GlfT2, a bi-functional UDP-galactofuranosyl transferase, the fatty acid synthase Fas, the pantothenate kinase PanK, a glutamine-synthetase adenylyltransferase GlnE and the sensor histidine kinase DevS.

However, these results are complicated by indirect effects - a single miRNA may target many mRNA targets that may influence other genes, thus negative correlation between miRNA and targets does not indicate a direct interaction between miRNA and target.

Examination of the genes regulated by BRDT yields many possible targets that could in part explain the morphologically abnormal sperm produced by the BRDT mutant testes.

This model may also enable to identify many therapeutic targets that can be used in the treatment of inflammations and disorders due to heat-related illnesses.

Over the last few years, many gene targets that regulate apoptosis, proliferation, and cell signalling have been identified, and numerous novel compounds have entered clinical trials either as single agents or in combination with cytotoxic chemotherapy.

Thus, miR-125b might have many other targets that remain to be discovered in future.