Sentence examples for many target organs from inspiring English sources

Polycyclic hydrocarbons affect many target organs and usually produce cancers at the site of exposure.

(ii) Etheno-adducts progressively increased in many target organs and preneoplastic lesions of cancer prone-patients and rodents.

Exposure to low level of lead in environmental manner has been reported to cause dysfunction in many target organs.

Indeed, EtOH alone exerts immunomodulatory effects and induces alterations in downstream TLR signaling in many target organs, such as the liver, the brain, and the gastric mucosa [ 41, 42].

In addition, this study is one of first that concerns vitamin D status in pregnant women in Sweden; it has shown that 25(OH D deficiency also exists in younger Swedish women during spring, and confirms that Somali Swedish women are often severely deficient in vitamin D, with important consequences for many target organs.

The chemicals 3 H-1,2-dithiole-3-thione (D3T), 4-methyl-5-pyrazinyl-3 H-1,2-dithiole-3-thione (OLT) and 5-tert-butyl-3 H-1,2-dithiole-3-thione (TBD) are dithiolethione class chemopreventive agents that have been shown to inhibit chemical toxicity and carcinogenicity in many target organs (1).

In addition to its ordinary clinical applications such as hypovolemic shock treatment, many investigators have attempted to utilize HSA as carrier to deliver various drugs to their specific target organs.

This stable nanoliposomal formulation has been shown in preclinical studies to improve pharmacokinetics and tumour bio-distribution of both irinotecan and its active metabolite SN-38 when compared with the free form of the drug, with less accumulation in many of the target organs associated with toxic side effects.

This raises serious concerns about the prospects of having to care very soon for both patients with higher-than-optimal BP and many more with target organ lesions subsequent to longstanding hypertension.

Estrogens play important roles in growth, differentiation, and maintenance functions of many target tissues in the female reproductive organs (Couse and Korach 1999).

For some applications, the success of gene therapy depends on the efficiency of gene transfer into target organs, however, delivery to many tissues is limited.