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They won't be able to afford many more such failures.
A major flaw in many such studies is a failure to consider fully the nature of the established microflora, which is to be modified pre-, or probiotically.
The promotion of biofuels as an alternative source of clean energy, for instance, has led Ghana and other countries to put vast tracts of prime agricultural land under cultivation for biofuel feedstock, but the failure of many such ventures has left land unsuitable for farming.
Flex fatigue, as possibly the single most important phenomenon by which cyclic bending under low stress takes place, has attracted the attention of many researchers where desire to reproduce such failures has resulted in a number of imaginative and original testing apparatuses.
Refractoriness is clearly a major factor in many such patients, possibly due to a failure of frontal control mechanisms or possibly through inappropriate regulation of cholinergic neuromodulatory mechanisms.
"Many of these failed calls originated in urban or suburban areas, and such failures affect all of us negatively".
As a result I developed Brill's Law of Catastrophic Failure: Catastrophic failure is never the result of a single event or interaction, such failures are the result of at least five, and as many as 10, interactions.
There are many such stories and the point is always the same: Don't allow fear of failure to stop you.
Many such assessments are merely a cursory documentation, often non-quantitative, of the extent and type of slope failure.
Such failures have happened previously.
And such failures are hardly unusual.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com