Sentence examples for many substantial problems from inspiring English sources

So the new model (2.1) can better imitate many substantial problems in the real world.

Based on our assessments of the documents we could obtain, we came to the conclusion that there were substantial problems with the design, conduct and availability of information from many of the trials".

Despite the beneficial effects, BCG vaccination does not prevent substantial problems with pulmonary disease in the adult population, especially in many developing countries [1].

The EU faces substantial problems.

There are substantial problems to solve".

Intermingled with the smaller colonials are many substantial houses.

Therefore, this approach may face substantial problems.

Despite the substantial problems identified, the team was disbanded.

Like many critics, he felt that "as a piece of storytelling, the unfolding of a mystery, the first half of Keeper of the Flame is a damn good show", but the rest of the film had substantial problems.

In one in four cases there was a "clinically important delay" before the patient was seen by a consultant, access to CT and MRI scanning is a "substantial problem" at many hospitals and in one in five hospitals "do not attempt resuscitation" orders were signed by "very junior trainee doctors".

Increased long-term sick leave is a substantial problem in many countries, and a major reason for this increase is generally believed to be related to psychosocial stress [1], [2], [3].