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Almost twice as many study patients died during the evaluation period compared to comparison patients (60.3% vs. 31.1%, P < 0.001).
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In many studies, patients with maximal back pain tend to have the greatest improvement in pain score after vertebroplasty more so than those with a lower degree of pain and there has been concern that the level of pain in the patients in the RCTs cited was lower than in most patients with vertebral fractures.
Also, many studies included patients over 65 years and not only very elderly patients [ 4, 22].
In the past, many studies reported patients per centre, resulting in a small number of patients per study.
Although many studies on patients with AKI who require dialysis have been performed, the literature is rather limited regarding AKI patients who do not require dialysis.
Meanwhile, many studies included patients who did not have SIRS.
Many studies of patients with alcohol dependence (AD) have highlighted their difficulty in identifying both their own emotional state and those of a social partner.
Furthermore, many studies mixed patients with short duration of the disease with those suffering from chronic CRPS.
Many studies exclude patients with significant comorbid conditions [ 33].
Many studies include patients with an ECOG performance status grade of 0 and 1 only.
Many studies include patients with ethnic variations that may influence the results.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com