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Iron ions (Fe2+) have been shown to be cariostatic in many studies particularly by their ability to reduce bacterial metabolism.

In addition many studies, particularly those regarding health-care contacts [9 11], are based on clinical samples, and there is thus a need for population-based studies in this area.

12 Many studies, particularly in CHF, have generated multivariable regression models describing factors most important in predicting readmissions.

Many studies, particularly those involving secondary transfer of patients who have suffered traumatic injuries, have found that air transport was time saving [ 59- 62].

However, all of these features have been disputed and it is likely that ascertainment bias will affect the conclusions of many studies, particularly those that focus upon single cases.

Details are given in the flow diagram of figure 1 Many studies, particularly those using routine data, use area-based deprivation data such as the Townsend 20 and Carstairs 17 scores, the UK Indices of Multiple Deprivation (IMD) 19 and the Jarman Index.

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Hillslope shape effects on overland flow and subsurface flow have been demonstrated by many previous studies, particularly in arid and semiarid regions.

DisEMBL is thus useful for target selection and the design of constructs as needed for many biochemical studies, particularly structural biology and structural genomics projects.

The implantation of a nuclear facility, such as ITER (about 20 buildings on 40 ha) requires many preparatory studies, particularly with respect to underground characteristics, topography, layout, deforestation, excavations, networks, fences and roads and impact of seismic hazard on design.

Many language studies, particularly in fMRI, use the subtraction paradigm, in which brain activation in a task thought to involve some aspect of language processing is compared against activation in a baseline task thought to involve similar non-linguistic processes but not to involve the linguistic process.

Many evolutionary studies, particularly with the increasing number of available genome sequences, use DNA sequence information solely to infer similar enzymatic or other function.

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