Sentence examples for many splice isoforms from inspiring English sources

ATG16L1 has many splice isoforms and a small number of these do not utilise the intronic sequence deleted in this gene targeting.

Following the initial identification of VEGF (Senger et al, 1983) many splice isoforms were subsequently identified, eventually forming a family of mature peptides – the VEGF xxx family (see Figure 1) (Houck et al, 1991).

This indicates that many splicing isoforms are only expressed in a small number of HeLa S3 cells.

This may in part reflect the exclusion of many splicing isoforms, owing to a lack of adequate experimental support, in the RefSeq database [ 47].

Either the RT-PCR is not working as intended or there are potentially many other splice isoforms present.

It remains unclear how many of the splice isoforms identified are sufficiently stable to result in translation products.

Second, aided by improved sequencing technology and increasing EST and cDNA experimental data, many more alternative splice isoforms had been identified [ 17, 18].

However, alternative splicing shows tissue specificity and is particularly important in neural development, with many neuronal-restricted splice isoforms identified, so the mechanisms here could be restricted to neural tumors.

CAPN3 exists in many alternatively spliced isoforms.

Our results showed that SUM-52PE cells overexpressed many alternatively spliced isoforms of FGFR2 at both the transcript and protein level as compared with normal HME cells.

Unlike other classes, a low level of variance was observed in the number of CRY-DASH genes, which suggests that these genes do not have many alternative splicing isoforms.