Moreover, none of the many specific skin AGE molecules correlated consistently with any specific CAC, carotid IMT or CMRI outcome, undoubtedly reflecting the complex pathogenesis of CVD in T1DM.
Considering the green molecule has only a few nonspecific contacts with the DNA whereas the orange molecule has many specific contacts and closely resembles the high-affinity structures determined previously with dsDNA, these structures appear to represent lower- and higher-affinity states, respectively, and will be referred to as such.
However, it is necessary to keep in mind that there are many valid critiques for the development of specific molecules to prevent cancers.
Many chemical compounds have been developed to inhibit specific molecules; in fact, they have contributed to unveiling the details of a variety of biological processes.
In each case, there is specificity: specific markers, specific genes, specific molecules specific antibodies, specific targets.
Genes can be specific difference makers because many specific differences in the sequences of nucleotides in DNA result in specific differences in RNA molecules.
Many cancer therapies are targeted, relying on drugs that block the spread of cancer by interfering with specific molecules involved in the growth and progression of certain tumors.
The work involves finding drugs to block specific molecules that these tumors need to grow.
Molecules that latch onto specific molecules -- carbon monoxide, hydrocarbons or, more ambitiously, a piece of DNA -- can be attached to the outside of a nanotube.
In the work that earned him the Nobel Prize, Dr. Cram created molecules with hollow regions where specific molecules could attach, much as a key fits into a lock.
