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Many specific genes from Psg were clustered in the genomes.
Accordingly, many specific genes targeting various lipid metabolic pathways were modulated by both PPARγ and PPARα/γ agonists, in at least several human hepatocyte donors and for some concentrations (Table S3).
Strikingly, the most significant similarly regulated genes after both stimulations are found down-regulated and many specific genes appear to be up-regulated.
Morphologic and biochemical studies have indicated that squamous differentiation is a multistage process and involves the sequential expression of many specific genes including keratins (3, 4).
Many specific genes that are potentially involved in the regulation of oocyte maturation, egg developmental potential, and embryo survival were identified by microarray and quantitative real time PCR (RT-qPCR) analyses [ 3, 27, 28].
However, the moderate value of the Spearman rank correlation coefficient (0.63), indicates that this positive correlation is not strong enough to consider the level of mRNA alone as a reliable predictor of protein levels for many specific genes.
Similar(49)
There are many specific defense genes that have been identified and regulatory aspects of their activities have been elucidated in many cases [ 1, 5].
The recently published A. mexicanus genome identified many specific candidate genes under eye-related QTL, and revealed expression differences in several development stages [ 6].
In many cases, specific genes are highly dynamic, and the principles governing their movements and interchromosomal interactions are currently under intensive study.
Expression of many lineage specific genes seemed to be controlled by histone modifications.
Furthermore, our results also indicate that NR1D1 serves a role in the activation of many photoreceptor specific genes.
More suggestions(15)
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