Sentence examples for many somatic cells from inspiring English sources
A single genetic locus is unlikely to predispose many somatic cells to tumour formation unless a fundamental molecular defect for example, related to DNA repair is present.
When this deletion is present, it is observed in many somatic cells and is often associated with structural defects such as microcephaly, micropthalmia and several skeletal and genitourinary abnormalities3,4.
The cell cycle of hPSC is relatively fast compared to many somatic cells (Becker et al., 2006), and high expression of SAC components may play a role in aberrant divisions as was observed in cancer cells.
Finally, many somatic cells live and evolve in environments teeming with diverse fast-evolving microbes.
Similarly, many somatic cells can be directly reprogrammed to other cells without a stem cell state.
Both the differences in the dynamics and the reported variations in global nuclear distribution patterns suggest that H1 variants such as H1.2 and H1.4 (the major H1 variants in many somatic cells) could have specific functions.
This was a surprising finding and indicated that direct lineage reprogramming may be applicable to many somatic cell types and many different directions.
On the other hand, stem cells may utilize different mechanisms or adaptations that confer on them some aspect of uniqueness or "stemness". In this case, stem cells will not exhibit the same coupling with the cell cycle as in many somatic cell models.
Ultimately, allowing the progressive differentiation and specialization of embryonic cells during development to form the many somatic cell types of the adult in an ordered manner.
NPC-associated HEZs occur as the distal parts of an interconnected system of a largely chromatin-free space traversing the nucleus of many somatic cell types.
Human iPSCs that morphologically and functionally resemble human embryonic stem cells (ESCs) have been generated from many somatic cell types by viral vectors expressing defined reprogramming factors since 2007.
