Sentence examples similar to many sites of replication initiation from inspiring English sources

As such, various scales of chromatin folding have become vital components of replication regulation such as influencing sites of replication initiation.

These results are consistent with the possibility that evolutionarily conserved elements define functionally active chromatin available as preferred sites of replication initiation.

This finding suggests that other yeast species may have also evolved distinct functional paradigms for selection of DNA sequences as sites of replication initiation.

Here, using a sensitive assay to monitor nascent DNA synthesis in early S phase, we identified thousands of replication initiation sites in cells before and after induction of the oncogenes CCNE1 and MYC.

Identification of replication initiation sites, termed origins, is a crucial step in understanding genome transmission in any organism.

Termination sites are locally the latest replicating regions, but the stochastic nature of replication initiation makes it difficult to locate termination sites from ensemble replication timing data (de Moura et al., 2010).

These results suggest that the increased probability of replication initiation at conserved intergenic sites must be determined by another as yet undescribed property of these regions.

Although the roles of many proteins involved in the initiation of replication are understood, the role of MCM10 remains controversial., A key process of replication initiation is to convert inactive MCM2 7 to active Cdc45-MCM-GINS (CMG) replicative helicase.

Genome-wide analysis of re-replication reveals inhibitory controls that target multiple stages of replication initiation.

Specific locations in the genome, called origins of replication, are sites of DNA replication initiation during S phase.

In this report we studied the efficiency of pre-RC assembly and site-specific replication initiation in the context of mini-EBV genomes.