Sentence examples for many significant alterations from inspiring English sources

Thirdly, and related to the second point, is the observation that OVH led to many significant alterations in cell metabolism (as evidenced by mRNA levels for relevant molecules) at six and 14 weeks post-injury, but these changes did not translate into overtly altered recovery of mechanical integrity.

Although many studies have shown significant alterations in the expression and activity of different cytokines and their signaling systems in liver cirrhosis and HCC, the critical components linking inflammation and liver cancer are only beginning to be unmasked.

Because of their potent self-renewal capacity, MSCs can be passaged many times without significant alteration of their major properties.

Pregnancy is associated with various physiological changes which may lead to significant alterations in the pharmacokinetics of many drugs.

TB has been shown to be associated with significant alterations in the levels of many serum proteins [ 6].

Whole genome transcriptome profiling of animal lungs revealed significant alterations in the expression of many genes with functions in cell adhesion and migration, channels, receptors, differentiation and proliferation, and, most strikingly, aspects of the innate immune response.

However, in contrast to the controls, in the welder group many GO bioprocesses were found to be significantly enriched with genes having significant alterations of expression after exposure to metal fume.

Over the past few years, significant alterations in the miRNA expression profiles between HCC and nontumor tissue have been demonstrated in many studies.

Sun also sold licenses to companies that made significant alterations, known as forks, as Google did.

According to the New York Post, they are considering "significant alterations to their home uniforms in 2010".

Mr. Somers found evidence of significant alterations, concluding that the table could not be 18th century.