Sentence examples for many rodent models from inspiring English sources

Many rodent models fail to replicate both MetS and NASH.

This size disparity is further emphasized in many rodent models of SCI that use thin incisions (hemisection), a problematic tactic often used for studying cell types with lower efficacy [1].

Many have proposed that rapamycin is a mimic of calorie restriction which is the gold-standard for anti-aging intervention resulting in both extended life span and health span in many rodent models.

The beneficial effects of PPAR activation have been independently reproduced in many rodent models of traumatic injury and neurodegenerative disease and there are several potential mechanisms through which PPAR activation promotes CNS repair and functional recovery.

Although the aforementioned studies point to a simple cause and effect relationship between the GH/IGF-1 axis and lifespan, experiments in many rodent models point to more complex interactions.

Understanding the cell origin and molecular mechanisms involved in its onset and progression is a major step towards the development of novel drugs against pancreatic adenocarcinoma, and many rodent models have been developed during the last ten years.

In early life, rodents fed a caloric restriction diet have lower IGF-1 levels than rodents fed a normal chow diet, and many rodent genetic models with a prolonged lifespan have lower levels of serum IGF-1 or IIS signaling compared to control groups [ 5- 7].

Silymarin prevents liver disease in many experimental rodent models, and is the most popular botanical medicine consumed by patients with hepatitis C. Silibinin is a major component of silymarin, consisting of the flavonolignans silybin A and silybin B, which are insoluble in aqueous solution.

Investigating rheumatoid arthritis mechanisms in animals is difficult; therefore there are many different rodent models which can more or less mimic the main symptoms of the disease (Bevaart et al., 2010; Zhang et al., 2012; Boettger et al., 2010).

When histological and physiological resemblance to humans is considered, a model with pigs may offer many advantages over rodent models.

Indeed, there are many examples of rodent models that are in fact less anxious than their respective controls, but still display social deficits (76, 77).