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There are also many reported examples of natural and experimental bacterial populations with higher than standard mutation rates [22] [26], showing that there are multiple situations in Nature in which being a mutator confers a selective advantage.
Despite this, there exists in the literature many reported examples of such regulators of DR. These include the histone deacetylase Sir2p [14] [16], the protein kinase AMPK [17], the serine/threonine protein kinase TOR [18], [19] and histone deacetylase Rpd-3 [20], along with the transcription factors PHA-4 [21], SKN-1 [22] and DAF-16 [17].
Our results demonstrate that a single suboptimal splice site is sufficient to distinguish a pseudoexon from a functional exon, and it is in line with the many reported examples of pseudoexon activation caused by single nucleotide substitutions that strengthen a weak splice site [ Buratti et al., 2006].
(4) There are many reported examples of high-throughput assays in which 3D spheroids are distributed in the wells of 96-well plates [20], [41], [42].
There are many reported examples of heterogeneous nucleating agents on protein crystallisation [13], [14] and a specific surface interaction that leads to either a promotion or an inhibition of crystallisation for some proteins is perhaps the most likely explanation for the observed interaction between plate make and protein.
There are many reported examples of nanoscale surface patterns that promote contact guidance and/or trigger changes in cell morphology.
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Many studies have reported examples of negative regulation (61,65).
Whilst many reported, for example, that they no longer slapped their wives, some still would not allow their wives to work outside the home.
For example, many reported IPV inquiry and/or identification rates from chart audits, rates of self-reported IPV enquiry, or the quality of IPV or CM case documentation.
But the strife, an unusually severe example of many reported clashes over farm taxes in recent years, was also a symptom of a deep economic malaise with no simple answer.
Many reports, for example, present only perinatal mortality data and do not distinguish between stillbirth and neonatal mortality.
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