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Complex metabolic networks are characterized by a great number of elements and many regulatory loops.
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It is involved in many regulatory feedback loops through the cooperative activity of its two ubiquitin-editing domains [ 9].
To begin to develop intuition for the mechanism of loop formation in the extremely short loops exhibited in many regulatory architectures, we have examined three different lengths: 89, 94 and 100 bp.
Many gene expression networks contain negative regulatory loops that act to restore expression to physiological levels upon perturbation of pathway components (Becskei and Serrano 2000).
In real biological system, many regulatory mechanisms, like positive and negative feedback loops have great impact on the gene expression levels.
Many regulatory departments have overlapping mandates.
In many regulatory jurisdictions these units can be employed without requiring specific regulatory consents.
However, the same fundamental concepts apply in many regulatory contexts.
They are a minimal representation of the regulatory principles, potentially representing overall effects of more complex, indirect regulatory loops.
For cell biologists, analysis of the regulatory loops which regulate cell proliferation is always fragmentary.
Reciprocal regulatory loops thereby consist of the metabolic, cell-division, circadian and seasonal oscillations.
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