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Advocates of such clinics highlight the many randomized clinical trials that show the efficacy of such clinics in reducing mortality and rehospitalisation [ 3, 18- 31].
Intra-articular (IA) injection of morphine has been the subject of many randomized clinical trials (RCTs).
He summarizes: "No matter how many randomized clinical trials have been done on a particular topic, about half the clinical trials cite none or only one of them".
Many randomized clinical trials use media techniques, direct patient contacts, and contact with health care providers, with mixed success [ 13].
Many randomized clinical trials have been performed comparing the body composition and metabolic effects of different antiretroviral combinations in the management of previously antiretroviral-naïve subjects.
Many randomized clinical studies did not find benefits on severe infections or sepsis after vitamin D normalization in vitamin D deficient patients [ 34– 34].
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The 6MWD has been used as primary endpoint in many randomized controlled clinical trials in PAH [ 1], and correlates with prognostic relevant clinical parameters such as WHO-FC in patients with SSc-PAH [ 6].
Nevertheless, crosstalk between the lung and brain is poorly understood [ 22], and although many randomized controlled clinical trials have evaluated the efficacy and safety of various methods of MV in ARDS and ALI patients, few studies have explored the influence of MV patterns at the neuronal level.
But many careful randomized clinical trials have not shown any benefit against heart disease, cancer, or other illnesses.
Despite the many published randomized clinical trials (RCTs), a substantial number of reviews and several national clinical guidelines, much controversy still remains regarding the evidence for or against efficacy of spinal manipulation for low back pain and neck pain.
In Western countries, twenty individual antiretroviral drugs, four fixed dose two-drug combinations, and two fixed dose three-drug combinations are available and many prospective, randomized clinical trials were performed to assess the efficacy and safety of HAART.[2] All these robust evidences were utilized to constitute the guidelines for occidental HIV/AIDS patients.
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