Moreover, therapeutic strategies to lower adenosine levels or inhibit adenosine receptors lead to improvement in pulmonary pathologies in many of these animal models [23], [24], [27], [29], [30], [31].
The results and conclusions will prove to be of value not just for health administrators in this country, but many other regions that share similarities in patterns of pulmonary pathologies.
This book describes various aspects of current scientific interest in clinical developments and management of pulmonary pathologies.
Other pulmonary pathologies: There are reports on the use of ultrasound in children to diagnose or distinguish among different pulmonary pathologies.
A variety of pulmonary pathologies, in particular interstitial lung diseases, are characterized by thickening of the pulmonary blood-gas barrier, and this thickening results in reduced gas exchange.
Pulmonary pathologies, such as inflammation, fibrosis, and edema, which cause an increased blood-gas barrier thickness, impair the efficiency of this exchange.
NCDs increasingly take their toll in Western Africa in the form of cardiovascular diseases and pulmonary pathologies.
Although mouse models have proven useful for TB drug discovery, many mouse strains fail to accurately reproduce the pulmonary pathology observed in human disease.
The discovery of polymers in broncho-alveolar lavage fluid and pulmonary tissue (11, 12), the pro-inflammatory nature of such extracellular polymers (11, 13) and their identification many years after liver transplantation (14) led to the proposal that pulmonary pathology could be induced by polymer-induced toxic gain-of-function with inflammation as an additional mechanism (15).
Many of these patients are already compromised due to acquired or pre-existing pulmonary pathology, and clinical respiratory distress may be masked by concomitant respiratory support and sedation.
