GoLoco motifs present in many animal proteins specifically bind to α-subunits of the Gi/o subclass of heterotrimeric G proteins [ 3].
This method, however, yielded few useful results for gaseous GAs, because they associate with many proteins non-specifically (they bind to more than one sites).
Recent studies on monogenetic inherited nephrotic syndrome (NS) and primary NS have revealed many protein molecules specifically expressed in podocytes, such as nephrin, CD2AP, podocin, and TRPC [ 5– 7].
Many other dsRBD proteins specifically bind to dsRNA duplexes, whereas some also weakly bind to DNA RNA hybrid duplexes.
In contrast to this proposal, our phylogenomics analyses have identified 31 proteins that are uniquely present in virtually all methanogens, as well as many proteins that are specifically shared by different subgroups of methanogens.
Conversely, many proteins that were specifically expressed in different age and gender groups might function to regulate the physiological states of the human body and adapt to the specific microbial community in the oral cavity.
A characteristic feature of Drosophila spermiogenesis is that many proteins are stage-specifically translated from stored silent mRNAs synthesized before meiotic divisions (for a review, see Renkawitz-Pohl et al., 2005).
We also describe the maintenance of single gene copies for many proteins involved in homologous recombination, specifically in DSB formation, recombination initiation, strand invasion and Holliday junction resolution.
None of the LaeA homologs share domains found in many protein methyltransferases that specifically act on histones, e.g., SET domains found in Clr4/DIM-5/Suvar3-9 Clr4/DIM-5/Suvar3-9 Clr4/DIM-5/Suvar3-9 2004; Adhvaryu et al. 2005).
Second, as discussed below, using this procedure we found co-eluting with Bcl-xL many proteins known to be able to specifically interact with Bcl-xL.
