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The advances in sequencing techniques and the accumulation of many protein sequences without the purified protein challenge the development of computer algorithms to identify dominant T-cell epitopes based on sequence data alone.
All numbers in this study are dependent on how many protein sequences have been discovered to date (2007).
Where genes have been located, the biological functions of many protein sequences are as yet undetermined (Carroll and Pavlovic, 2006).
L. multiflorum and L. m. westerwoldicum have the smallest number of species - specific proteins, and many protein sequences that are shared only between these two.
The vinegar fly (D. melanogaster) came fourth despite the fact that ca. five times as many protein sequences from D. melanogaster have been deposited in the nr database as compared to sequences from A. aegypti (Additional file 1).
Many protein sequences have been shown to self-associate and assemble, though these reactions are often induced by nonphysiological conditions, including extreme shifts in buffer composition and pH, salt, temperature, or extended incubation periods.
Similar(50)
The idea of implicitly using more than one amino acid has been around for some time (Nagano, 1973; Chou and Fasman, 1978), but many protein sequence comparison methods, when making a prediction, implicitly treat positions in a protein sequence with some level of independence.
The results show that for many long protein sequences, it is very hard to find homology structure templates of the full chains.
Therefore, our method can serve as a useful high throughput tool for annotating the functions for many uncharacterized protein sequences.
(3) Although a web-server for Euk-mPLoc has been established at http://www.csbio.sjtu.edu.cn/bioinf/euk-multi-2/, only one query protein sequence at a time is allowed when using the web-server to conduct prediction; for the convenience of users in handling many query protein sequences, such a rigid limit should be improved.
A common characteristic of many regulatory protein sequences is the presence of phosphorylation sites.
More suggestions(15)
multiple protein sequences
many protein functions
many protein variants
many protein isoforms
many action sequences
many protein translocases
many protein regulators
many protein pairs
many protein enzymes
many protein features
many protein targets
many protein systems
many protein fragments
many protein kinases
many protein components
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