Sentence examples for many protein isoforms from inspiring English sources

How many protein isoforms are detected that fulfil the 2 peptide criteria?

However, lack of conservation can also mean that many protein isoforms have a confined, species-specific function rather than no function at all.

As alignment cost increases in a nonlinear manner with the number of sequences, the Cons approach rapidly becomes prohibitive for larger gene families with many protein isoforms.

We show that the loss of PTBP2 leads to a catastrophic failure in neuronal maturation and to the misexpression of many protein isoforms affecting neurite growth, synapse formation and synaptic transmission.

Because many genes encode multiple protein isoforms, not all coding-intron insertions are equally useful.

In addition, a cDNA library generally covers a larger portion of the proteome, including multiple protein isoforms for many genes.

The majority of eukaryotic genes can produce different transcripts due to alternative splicing or transcription initiation, and many such transcripts encode different protein isoforms.

If the AS event is located in the coding region of these transcripts, the resulting protein isoforms will in many cases differ by an indel (only these type of sequence variations were considered in this study).

In humans, more than 90% of genes encode multiple protein isoforms [ 2], and many diseases are caused by the dysregulation of splicing patterns [ 3].

Thus, expansion of adipose tissue during obesity or its normalization by rimonabant treatment may require not only changes in level of expression of many genes but also the production of new protein isoforms issued from differential mRNA splicing.

A delay between mRNA abundance and protein detection is observed for 63.7% of 237 protein isoforms (it is unclear how many of the 125 genes analyzed this represents).