Sentence examples for many probe design from inspiring English sources

Considering that microarray experiments are non-equilibrium measurements, it is desirable that microarray probes exhibit uniform thermodynamic properties, which many probe design tools aim to achieve by demanding a narrow distribution of the probe-target melting temperature Tm.

Many aspects of probe design are open to manipulation, and in practice probes can be successfully designed for most target sequences of interest.

In the pan-microbial microarrays, many probes are designed for one pathogen, and there is no way to confirm each probe.

Therefore, commercial expression arrays could in principle be used for the task, especially because many probes are designed on the 3'-untranslated regions of the transcripts, which are particularly divergent across species [ 10].

In a nutshell, many instances of a unique probe design are synthesized onto a group of adjacent discrete features or cells on the GeneChip.

Careful considerations were given to the probe design to reduce many error sources.

Target-specific probe design is a prerequisite for many applications, i.e. a single nucleotide polymorphism being surrounded by the probe sequence.

The low depth of coverage and short length of 454 sequence reads have also created new challenges for probe design, i.e., too many unique sequences (both contigs and singletons).

Many of these caveats are related to the probe design and can be alleviated for future rat experiments by improving the rigidity of the probe and by reducing source detector separations.

However, MLPA probe design is a time consuming process requiring many steps that address multiple criteria.

In course of probe design for DNA microarray development, each of the markers yielded a high number of potentially species-specific probes in silico, although many of them were rejected based on microarray hybridisation experiments.