Sentence examples for many posttranslational modifications from inspiring English sources
This modification is only an initial example, as its design is amenable to incorporate many posttranslational modifications or allosteric regulations that are necessary to facilitate protein interactions.
Like many posttranslational modifications with regulatory functions, mono-ADP-ribosylation of arginine is a potentially reversible process.
In this study, we used Position Specific Iterated BLAST [ 25] (PSI-BLAST) to quantify the sequence conservation with Position-Specific Scoring Matrix (PSSM) which has been demonstrated to be effective for the identification of many posttranslational modification sites [ 26– 30].
There are many different posttranslational modifications of proteins, such as phosphorylation, acylation, methylation, glycosylation, glycation, truncation, ubiquitination, and oxidation.
This indicates that, as with many other posttranslational modifications of histones, also the H3-K27me3 mark needs to be 'read' and 'translated' into the appropriate functional output and posits a more complex and nuanced set of functions for PcG proteins [9].
Fine-tuned functions should therefore mainly result from the many possible posttranslational modifications and the sequence differences between duplicates.
This yeast expression system has become increasingly popular as it represents a valuable and cost-effective tool for protein engineering studies with potential of performing many of the posttranslational modifications typically associated with higher eukaryotes (reviewed in [ 14]).
As colon cancer is the effect of accumulation many somatic mutations in oncogens, supressors, mismatch repair genes and many genes responsible for posttranslational modifications of proteins, multidirectional approach should be applied for its detection.
Many proteins carry multiple posttranslational modifications.
Additionally, many sites of various posttranslational modifications have been identified in p53.
Despite the many types of possible posttranslational modifications (PTMs) in RiPPs, RiPP pathways share some nearly universal features.
