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Another approach is to use target-prediction methods to predict the bioactivity of a single molecule against many possible targets.
Examination of the genes regulated by BRDT yields many possible targets that could in part explain the morphologically abnormal sperm produced by the BRDT mutant testes.
The NFκB pathway is complex and contains many possible targets for inhibition.
Based on sequence similarity many possible targets were also identified for the soybean miRNAs.
A high mutation rate is consistent with the complexity of flowering time genetic determinism, with many possible targets for selection [ 57].
There are many possible targets of the JNK signaling pathway that may affect the mitochondria, including members of the Bcl-2 group of apoptotic regulatory proteins (Tournier et al. 2000).
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However, this study suffers from the fact that it has been conducted in transgenic Arabidopsis, with a smaller genome, thus missing many possible target genes.
Analysis results indicated that 874 miRNAs with MFE ≤ −20 and Score ≥ 150 interact with many possible target sites in 248 TPGs and their cognate genes and might potentially co-regulate this pair of TPG and parental gene (Supplementary File 2).
Clearly, there are many possible therapeutic targets, but inhibition of cytokines appears to offer an especially efficient approach to suppressing inflammation and preventing joint damage [ 14].
Leicester is a hugely diverse city but I imagine that doesn't automatically make your job any easier… Of course it's complicated, as there are so many different possible targets and deciding which to pursue is a challenge in and of itself.
For the identification of potential miRNA targets of the screen hits we used three major databases of computationally predicted miRNA targets using different prediction algorithms to ensure finding as many potential targets as possible.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com