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The mPRα receptor has been associated with many physiologic functions in vertebrates.
Nonstandard work hours may be disturbed by many physiologic functions and systems that are circadian in nature (Akerstedt 1990).
Thus, consideration of the potential for non-dioxin-like AhR agonists to alter many physiologic functions (i.e., "toxicity") is warranted.
PPARγs appear to play a role in the regulation of many physiologic functions such as lipid metabolism, atherogenesis, inflammation and cellular differentiation[ 21, 22].
The hypothalamus pituitary adrenal (HPA) axis is an important system that regulates and integrates many physiologic functions in response to environmental stressors (Wingfield and Kitaysky 2002).
It is now recognized that many physiologic functions, including energy metabolism, exhibit 24-h circadian rhythms generated by light/dark cycles (1– 3).
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Importantly iron has many other physiologic functions that may be important for overall health such as immune function, thermoregulatory performance, energy metabolism, and exercise or work performance [ 10].
Given the pleiotropic effects of leptin in regulating appetite, skeletal metabolism, fertility, and many other physiologic functions, however, targeting leptin directly may prove overly complex as an osteoarthritis therapy.
Laminins are vital for many physiological functions.
Animals undergo substantial changes in many physiologic and biochemical functions as a natural consequence of aging.
Many anatomic and physiologic functions scale within or across species in accordance with the allometric relationship, y = axb.
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