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In this report, we found that many pathways involved in the silkworm physiological functions were changed after the infection.
There are many pathways involved in HIF-1 α affected autophagy.
There are most likely many pathways involved in the immune regulatory network that function to maintain IgE at low levels.
Many pathways involved in this gene cluster were also significantly recognized (P < 0.05): T-cell activation, endothelin signaling pathway, hypoxia response, and plasminogen-activating cascade.
Pathway analysis retrieved many pathways involved in cancer onset and progression as well as linked to specific tumors, as shown in Figure 5.
As RNA silencing represents one of many pathways involved in RNA degradation, bioinformatics analysis from a perspective independent of small RNA-guided cleavage is crucial for detailed understanding of degradome data.
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Moreover, cell adaptation to in-vitro microenvironments involves recalibrations of many pathways involving the cell surface, for example by genetic and epigenetic alterations [7], [8], different post-transcriptional regulation [9] and modified signaling networks [10].
Many pathways involving the innate and adaptive immune system, particularly cytokine signaling, also displayed significant enrichment.
HBV is a DNA virus that can integrate DNA into host genome thereby increase the yield of transactivator protein HBxAg that may deregulate many pathways involving in metabolism of cells.
The induction of EMT by TGF-β1 in the renal cells takes several days and requires the interplay of many pathways, involving SMAD proteins (Li et al, 2002), the integrin-linked kinase (Li et al, 2003) and Rho-family GTPases (Bhowmick et al, 2001; Masszi et al, 2003).
Among the many signaling pathways involved in maintaining GSC stemness, tumorigenic potential, and anti-apoptotic properties, the PDK1/Akt pathway is a challenging target to develop new potential agents able to affect GBM resistance to chemotherapy.
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many pathways implicated
many constituencies involved
many subspecialties involved
many cases involved
many processes involved
many egos involved
many variables involved
many nations involved
many steps involved
many risks involved
many actors involved
many parameters involved
many contributions involved
many people involved
many teams involved
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