Sentence examples for many pathways essential from inspiring English sources

Heterotrimeric G protein signaling is involved in many pathways essential to development including those controlling cell migration, proliferation, differentiation and apoptosis.

GSK3 is intricately involved in many pathways essential to cellular function.

This requirement has not been included in multiple previous studies of E. coli metabolic networks, including the published analysis of the iJR904 model [ 7], resulting in many pathways essential for in vivo viability of E. coli having zero flux in silico.

Remarkably, many pathways that are essential for the migration and lamination of cortical neurons during brain development involve PKs and lead to the phosphorylation of specific substrates (Ayala et al., 2007).

The link between stem cells and cancer cells is supported by increasing evidence that cancer can develop from stem cells, and that many cell signaling pathways essential for normal development are dysregulated in cancer (Catalina et al., 2009).

These results make sense, since genes that are part of many pathways often have an essential role or have several functions, suggesting a potential pleiotropic effect of mutations in these genes, and thus a higher chance for them to be deleterious.

Both PKC and AKT are protein kinases that are essential in many pathways controlling cell growth and apoptosis.

NOX-derived ROS is required for propagation of many pathways and the maintenance of essential stem cell populations in the brain.

Bax is a pro-apoptotic member of the Bcl-2 family that is essential in many pathways of apoptosis, as well as translocates to discrete foci on the mitochondria during the initial stages of apoptosis, which subsequently become mitochondrial scission sites.

The characterization of two discrete phases of cardiomyocyte differentiation in the zebrafish heart has important implications because many of the genes and regulatory pathways essential to embryogenesis are conserved between zebrafish and mammals.

The signaling events affected by many of the genes in this signature occur in pathways essential for the immune response and cell activation.