However, there were a lot of similarities between our data and the published work [ 24- 36], for example, regulation of many defense-related genes, many hormonal pathway genes, and cell wall modification genes.
Our analysis confirmed substantially downregulated expression of many Wnt pathway genes in aged versus young TECs, and extended previous findings to show that many of these genes are differentially regulated in c- and mTECs (Fig. 4D,D′).
Therefore, despite using the same secretory compartments as other cells, the dependence of neurons on the secretory pathway for synaptic transmission, outgrowth and remodelling of dendrites and axons, combined the vast distances involved, means the impact of mutation in many secretory pathway genes has a greater impact on neuronal, rather than non-neuronal, cell function [142].
Many IIS pathway genes were initially identified in C. elegans based on their regulation of dauer formation.
Many piRNA pathway genes also have been shown to adaptively evolve (Obbard et al. 2009; Kolaczkowski et al. 2011).
Earlier also, SA and JA have been shown to affect expression of many carotenogenic pathway genes [ 29].
In addition, many Wnt pathway genes are expressed within the mammary buds at E12.5 and E15 [ 4].
Additionally, transcripts related to Bet v I allergen family, antimicrobial protein, germin-like protein, and many photosynthetic pathway genes were also highly abundant.
In this study we report identification of many carotenoid/apocarotenoid pathway genes which were known from other plants but not isolated from Crocus.
Tobacco NtLIM1 has been demonstrated to act as a transcription factor and is able to bind the conserved PAL-box found in promoters of many phenylpropanoid pathway genes [ 64].
