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Lipids peroxides are likely involved in many pathological events, including inflammation, metabolic disorders, oxidative stress and cellular aging.
Many pathological events can trigger neuroinflammation and the primary insult can be infective, degenerative, metabolic or ischaemic.
TGFβ has been recognized as a central player in many pathological events related to CKD progression at the glomerular, tubulointerstitial and vascular levels.
Not surprisingly, many of the molecules that have been developed are used to target receptors on the endovascular region which are upregulated during many pathological events of the brain.
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Lipid peroxidation causes damage to unsaturated fatty acids, which results in decreased membrane fluidity and leads to many other pathological events.
Lipid peroxidation causes damage to unsaturated fatty acids, which results in decreased membrane fluidity and leads to many other pathological events [ 4, 50].
Reactive nitrogen species (RNS), such as nitric oxide and its higher oxides, play important roles in cell signaling during many physiological and pathological events.
Thus many physiological and pathological events are closely related to persistent protease activity.
Moreover, changes in glycan structures are associated with many physiological and pathological events such as cell growth, migration, and differentiation.
This pivotal molecule regulates many physiological and pathological events via controlling cell cycle progression and cell growth.
N-cadherin has been implicated in epithelial-mesenchymal transition (EMT), a process involved in many developmental and pathological events, including the formation of splanchnic mesoderm from primitive streaks.
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