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Attacking bacterial communications is just one of many approaches being pursued to develop new antibiotics, a major public health priority because many pathogens have become resistant to existing antibiotics.
Many pathogens have evolved to elude immunity and this has limited the utility of current therapies.
Many pathogens have evolved ways to "blind" the immune system, thus allowing them to go undetected and propagate freely.
More recently, in the light of computer-aided biotechnology and reverse vaccinology, the precise selection of antigenic peptides and rational vaccine design against many pathogens have developed.
The newly contagious, deadly virus could escape from the laboratory, as many pathogens have.
However, many pathogens have evolved methods to evade attacks by phagocytes.
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They also had to grapple with the fact that Neisseria, like many pathogens, has coat materials that shift in response to immune pressures, making it necessary to target multiple coat elements simultaneously.
The structural and functional conservation of the T3SSs across many pathogens has made it an attractive target for novel antibacterial therapeutics development with broad spectrum activity.
The involvement of lipoproteins in the infection processes of many pathogens has received wide attention [ 8].
Recently, high-resolution melting (HRM) for high-throughput analysis of many pathogens has been developed, for example, for variation scanning [ 9], genotyping [ 10] and species determination [ 11].
To the Editor: Emerging infectious diseases have caused catastrophic declines in wildlife populations, and the introductions of many pathogen have been linked to increases in global trade and travel (1 ).
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