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The 9p21.3 risk locus is the first locus to be associated with an increased risk of coronary artery disease (CAD -related events and many other phenotypes.
Many signals of association are close to, or within, previously known pigmentation genes from both human and model organism studies These allelic effects span a spectrum of OR and minor allele frequencies consistent with many other phenotypes with an underlying polygenic architecture27,28 (Fig. 4a).
It is also important to focus on the lack of association of rs2513280 with the many other phenotypes that might have been expected to demonstrate a link with galanin, based on the pre-clinical rodent findings.
In general, any two phenotypes of interest are embedded in a complex network and are affected by many other phenotypes not considered in the grossly simplified (and thus misspecified) pairwise models.
This has not happened, largely because drug response phenotypes, like many other phenotypes, are probably the net effects of numerous common genetic variants of small effect, and uncommon interacting variants of unknown effect size.
Importantly, today we can assert that many CNVs, which affect specific genes and chromosomal regions, can lead to susceptibility and predisposition to certain diseases such as HIV, lupus, nephritis, pancreatitis and psoriasis among many other phenotypes.
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The lack of strong genetic association with EPQ-N score might imply that neuroticism is controlled by many loci each of relatively small effect, as is the case for many other complex phenotypes.
Given the increasing public availability of genomic data, we predict that this approach to in silico drug discovery will be an attractive approach that could be fruitfully explored in many other disease phenotypes.
Nonetheless, many other brain phenotypes could easily be substituted, such as cerebellum, hippocampus, corpus callosum, and cortex size.
Nonetheless, we show that the heritabilities of these ADRs are similar to those of many other clinical phenotypes that have been highly successful in GWAS (i.e., diabetes, obesity, Crohn's disease, and schizophrenia).
Many other established phenotypes that differ between medaka strains have been observed during the previous century of research on this fish (Hyodo-Taguchi 1990; Ishikawa et al. 1999; Kimura et al. 2007), and further work will be needed to examine the suitability of this population for each phenotype.
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many other women
many other things
many other organizations
many other panelists
many other details
many other teams
many defective phenotypes
many debilitating phenotypes
many other questions
many other mysteries
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many other employers
many positive phenotypes
many other factors
many other countries
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