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The Reverend John Michell calculated in 1767 that the probability of a chance alignment of so many bright stars was only 1 in 500,000, and so correctly surmised that the Pleiades and many other clusters of stars must be physically related.
As complete genome sequences become available, we can begin to track the evolutionary history of many other clusters of evolutionarily related genes.
Figure 4a also shows that Proteny results in a much clearer synteny between the scaffolds than i-ADHoRe (Supplementary Fig. S6b), which includes many other clusters which occlude the results.
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These modules are widely ignored by many other clustering algorithms which calculate correlations over all samples.
There is also a way to approximate an optimum number of metagenes (see [ 17] and the Methods section), which is not true of many other clustering methods.
While many other clustering procedures could have been used, CPBA has the advantage of dealing with dissimilarity measures as opposed to numeric input variables.
Unlike many other clustering algorithms (e.g. k-means) where the number of clusters needs to be specified from the outset, AP clustering optimizes the number of clusters within the algorithm.
One of the unintuitive aspects of density-based clustering is that its performance tends to improve with the size of the input dataset, contrary to many other clustering approaches.
Among many other gene clusters, the blast yielded a biosynthetic gene cluster in Bacillus licheniformis DSM 13 (ATCC 14580) that encodes a lantibiotic prepeptide with apparent homology to mersacidin [14], which is a lantibiotic with promising anti-Staphylococcus activity [15].
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Many other bi-clustering algorithms, including Bimax and the recently described BiBiT (Rodriguez-Baena et al., 2011), discover only homogenous bi-clusters and have low tolerance to noise and missing data.
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CEO of Professional Science Editing for Scientists @ prosciediting.com