Physiologists have found that the performance of many organs such as the heart, kidneys, brain, or lungs shows a gradual decline over the life span.
Dysfunction of mitochondria, the energy-producing organelle of eukaryotic cells, may lead to mitochondrial diseases with severe symptoms in many organs, such as Leber hereditary optic neuropathy (LHON), mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS), myoclonic epilepsy and ragged-red fibres (MERRF), etc.
Fibroblasts are an abundant cell type, found in many organs such as the heart, liver and the skin.
This grafting site has been shown to be permissive for the development of many organs such as ovarian cortex, thyroid, skin and airway [25] [28].
The Paired (Pax) family of genes has been shown to control development of many organs, such as brain, ear, eye, kidney, muscle, pancreas and thyroid [1], [2].
Chronic inflammation has emerged as a potential risk factor for carcinomas in many organs such as the liver, colon, bladder, lung and pancreas [54], and there is compelling evidence supporting a role for inflammation in the pathogenesis of prostate cancer [55], [56], [57].
This tumor type has been detected in many different organs, such as the uterus, lung, hepatobiliary tract, gastrointestinal tract, and urinary tract [2 5].
When administered through veins, CNTs can directly get into blood circulation and distribute in many internal organs, such as liver, spleen, heart and kidney (unpublished date).
Although the esophagus is the most frequent location for carcinosarcoma [11], carcinosarcomas have been detected in many different organs, such as the uterus, lung, hepatobiliary tract, gastrointestinal tract, and urinary tract [2 5].
In severe infection, the virus production inside the body is greatly increased, and many more organs (such as the liver and the bone marrow) can be affected.
Other studies report the presence of H5N1 viruses in many extrapulmonary organs, such as intestine, liver, and brain [3] [7].
