Large and complex target volumes are surrounded by many organs at risk (OARs), such as the brain stem, spinal cord, and parotid glands.
PS1 is expressed in many peripheral organs as well as the brain [ 42, 43].
It has been detected in many internal organs, as well as in the synovial fluid and joint tissues of chickens with infectious synovitis [ 2– 4].
While the cells of the SCN contain large numbers of membrane receptors, they have also been found to be more widely distributed not only in the brain but in many other organs as well.
The circulating form, 25(OH) vitamin D, is made in the liver and is a best marker of vitamin D status (Rosen, 2011). 1 α, 25(OH)2 vitamin D is the most active form and mostly generated in the kidney, although can be made in many other organs as well.
Karroubi was Khomeini's personal representative to many important state organs, as well as a two-term Majles Speaker.
Chronic inflammation has emerged as a potential risk factor for carcinomas in many organs such as the liver, colon, bladder, lung and pancreas [54], and there is compelling evidence supporting a role for inflammation in the pathogenesis of prostate cancer [55], [56], [57].
Physiologists have found that the performance of many organs such as the heart, kidneys, brain, or lungs shows a gradual decline over the life span.
Dysfunction of mitochondria, the energy-producing organelle of eukaryotic cells, may lead to mitochondrial diseases with severe symptoms in many organs, such as Leber hereditary optic neuropathy (LHON), mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS), myoclonic epilepsy and ragged-red fibres (MERRF), etc.
