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However, many open issues can be evidenced regarding the true possibility of scale-up, as well as currently lacking information for process design and economical evaluation.
The delay-tolerant network (DTN) architecture envisions a protocol suite addressing many open issues in networking, and extending far beyond the current Internet suite's capabilities.
Synthetic biological logic gates have been previously demonstrated, but there remain many open issues in the design of sequential (state-holding) logic operations.
"It was not a given, we had many objections from many sides, and many open issues," government spokesman Pandelis Kapsis, said.
Significant progress has been made in evolutionary multi-objective optimization and multi-criteria decision communities, although many open issues still remain to be addressed.
Even though the large number of works already reported in the literature, there are still many open issues towards the design of robust and scalable geographic routing algorithms.
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Identity management is a broad domain that involves many open security issues and challenges including Openness, Identity Theft, Least Privileges, Elevated Privilege Control, Availability, Confidentiality, Integrity, Trust Management etc (Cloud Security Alliance SecaaS Guidance, Category 1: Identity and Access Management, 2012 by Cloud Security Alliance 2013).
One might have expected that in preparing the declaration, Iraq would have tried to respond to, clarify and submit supporting evidence regarding the many open disarmament issues, which the Iraqi side should be familiar with from the Unscom document S/1999/94 of January 1999 and the so-called Amorim Report of March 1999 (S/1999/356).
While e-health network reliability and security have been the focus of research in recent years, many open research issues remain, particularly as technologies advance.
They can be effectively applied also to nonlinear problems [37, 58, 59], even if this in turn introduces both numerical and theoretical complications, and many open research issues are still to be faced.
David Sandalow, the assistant secretary of state who negotiated the breakthrough with India, says, "Many of the open issues in the Kyoto treaty are gradually being ironed out".
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