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Angiogenesis plays a critical role in many normal physiological processes as well as in tumor neovascularization associated with cancer progression.
Extracellular matrix degradation is involved in many normal physiological processes including development, growth and tissue repair.
Angiogenesis plays a critical role in many normal physiological processes, as well as in tumor neovascularization [ 34].
Estrogens, especially 17β-estradiol (E2), play an important role in many normal physiological processes in mammals such as reproduction, cardiovascular health, bone integrity, cognition, and behavior [ 3].
Cyclooxygenase-1 is constitutively expressed in nearly all cell types and plays a central role in many normal physiological processes, such as cytoprotection of gastric mucosa.
Melatonin, a neurohormone, plays important roles in adjusting the 'biological clock', and is an important mediator in many normal physiological functions [ 1].
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These pathways are involved in many normal silkworm physiological metabolic processes.
Transmembrane proteins (TM proteins) make up 25% of all proteins and play key roles in many diseases and normal physiological processes.
There is also a growing body of evidence that implicates many immune-related genes in normal physiological processes eg. tissue remodelling [ 33].
This polarity, referred to as planar cell polarity (PCP), or tissue polarity, is essential for the normal physiological function of many epithelia.
NOTCH1 belongs to a unique family of type I transmembrane receptors that regulate cell fate decisions and differentiation during normal physiological development of many tissues.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com