Sentence examples for many new targeted from inspiring English sources

Eisenhauer described the challenges of clinical trials in the face of so many new targeted therapies, such as those targeting cell surface receptors and intracellular signaling pathways, including how to define efficacy, when to identify biomarkers, and how to choose which therapeutic direction to support.

Fortunately, the discovery of signal transduction pathways and their importance in a variety of cancers has led to the development of many new targeted agents.

This presumably contributes to why the success of so many new targeted molecular therapies is measured in additional months but not years.

The introduction of many new targeted therapies to clinical practice provides support for the role of intratumoural heterogeneity in the loss of drug sensitivity.

In addition, many new targeted agents such as imatinib and cetuximab are effective only if their respective molecular markers are available for pharmaceutical intervention.

Although it has been found that the tumour shrinkage usually implies efficacious treatment, this cannot be generalised to many new targeted treatments.

The small changes in score confirm initial trends, for many new targets and assays.

Epigenetics can offer many new targets for this approach.

Unexpectedly, many new targets were found to be 'promiscuous' as they were inhibited by a variety of different compounds.

We provide a rank-ordered comparison of MAPK specificity across the ETS family, confirm known targets and identify many new targets.

With the identification of many new targets of Zap1 activation, we are building a comprehensive picture of how yeast cells respond to zinc-limiting conditions.