Sentence examples for many neuronal functions from inspiring English sources

Based on the above studies that both NRG1 and BDNF regulate neural development, and NMDARs promotes many neuronal functions before synaptogenesis, we hypothesized that NRG1-induces NR2B activation in immature neurons from embryonic mouse cortex via BDNF/TrkB dependent mechanism.

The L1-CAMs are involved in many neuronal functions, including axonal guidance, neurite outgrowth and fasciculation, and cell migration (Chang et al., 1987; Lindner et al., 1983; Fischer et al., 1986; Maness and Schachner, 2007).

Therefore, the delayed maturation observed in many neuronal functions of RhoE null mice could be related to neurite outgrowth retardation.

Iron is essential to life and plays a role in many neuronal functions; various neurodegenerative diseases such as Parkinson and Alzheimer diseases are associated with iron metabolism deregulation [ 3, 4].

To conclude, our data indicate that many specialised neuronal functions are present in all CNS regions.

Endogenous melatonin plays an important function in regulating circadian rhythms for proper sleep-wake cycles as well as many neuronal and hormonal functions [105, 106].

We identified several sets of genes regulated downstream of FruM isoforms, including many annotated with neuronal functions.

Validated PTBP2-dependent splicing events include many transcripts with important neuronal functions, including the postsynaptic scaffolding proteins PSD95 (Dlg4) and gephryn (Gphn), the neurotransmitter receptor GABAA Rγ2 (Gand2), and the key calcium signaling molecules CamK2a and CamK2b.

Of those SNPs that effect a missense change in protein coding exons, many are associated with neuronal functions [for example, the CNS-restricted protein tyrosine phosphatase, receptor type 2 mutation (Ptprt, Chr. 2) limited to the LtJ substrain].

Moroz continues, "Hormonal-like volume transmission [see earlier] can serve many true integrative and neuronal functions without a specialized synapse … if targets are localized within a few micrometers from the transmitter release points".

However, the fact that both the sponge Amphimedon and the placozoan Trichoplax have many genes involved in typical neuronal functions [ 58, 74] suggests that many conditions required for the generation of a complex nervous system were already present in the last common ancestor of all animals.