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The cornea is an extremely sensitive tissue and contains many nerve fibres that respond to pain.
Demyelinating neuropathies are those in which the Schwann cells, which form myelin (the white, insulating sheath on the axon of many nerve fibres), are primarily affected and migrate away from the nerve.
Each commissure apparently consists of as many nerve fibres as the ventro-lateral cords and measures 3 4 μm in diameter.
doi: 10.7554/eLife.01482 Image Dorsally projecting motor axons in mutant mice Although many nerve fibres travel considerable distances as they develop, the motor axons that carry signals from the central nervous system to various muscles throughout the body must complete the neuronal equivalent of the Oregon Trail.
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Since many motor nerve fibres cross over and intertwine in the pons, the resulting swelling may lead to their compression and dysfunction, as well as to demyelination, a condition known as central pontine myelinolysis.
If it is very excitable, it will respond to impulses from many afferent peripheral nerve fibres; if it is relatively inexcitable, it will be affected only by those peripheral fibres that are connected to it and located near it.
Since many of the nerve fibres traveling from the hair cells to the brain are constantly active, this arrangement makes the receptors a highly sensitive detection system for both vertical and horizontal linear acceleration.
Many fine-calibre nerve fibres penetrated into the epidermis (IENFs), some extending almost to the stratum corneum (Fig. 2 a– c, ipsilateral paw pad skin).
Because many squid have brain nerve fibres that are hundreds of times thicker than those of humans, neuroscientists have long used them for research.
For years, neuroscientists had resorted to slicing cadaver brains into razor-thin sheets, scanning them, then putting the sections back together, trying to realign the nerve fibres, many of which had been damaged by being cut into layers.
All annulospiral endings were intensely labelled for mGluR5, and many intrafusal small-calibre nerve fibres were also mGluR5-positive (Fig. 6A' C' C
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