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There are so many negative unknowns".
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Furthermore, in disease pathogenesis there are many unknown unknowns - including mediators driving synovitis that are yet to be identified.
There are so many unknowns involved that many of them cannot even conceive of how they would cope.
Another juror, Fuzzy Trojan said nuclear waste storage had "too many unknowns and too many risks".
but here especially there are many 'known unknowns' and almost certainly quite a few 'unknown unknowns'.
"There are many, many unknowns," she went on.
There are too many known unknowns for comfort, given China's global weight.
But if you're thinking about spending your golden years abroad, there are many more unknowns.
And many fundamental unknowns remain.
There are so many more unknowns.
The fact I had so many complete unknowns was freaking me out.
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CEO of Professional Science Editing for Scientists @ prosciediting.com