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At the same time there aren't many mutations that can make us a whole lot smarter.
Because we found many mutations that potentially affect metabolism and growth in PAO6609, we used defined siderophore deletion mutants of the siderophores pyoverdine and pyochelin for these experiments.
The first genotypes able to perform complex functions differed from their non-performing parents by only one or two mutations, but differed from the ancestor by many mutations that were also crucial to the new functions.
Using this approach, we identified many mutations that were enriched in the post-treatment samples and some of these genes, such as NOTCH1, ERCC1, and STED2, have been previously reported to be associated with chemoresistance33,34,35,36.
Members of a cancer-afflicted Scandinavian family lack this section of the gene, which is one of many mutations that can boost the risk of cancer.
There might be many mutations" that contribute to an observed abnormality.
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When a new protein evolves in nature, the process usually requires many genetic mutations that are acquired over many generations.
As we have outlined, there are many other molecular pathways and many other mutations that could be explored.
The IDH-2 mutation is just one of many enzyme mutations that are found in acute myelogenous leukemia.
At the DNA level there may be many different mutations that affect gene-expression levels, but very few potentially beneficial mutations that directly affect protein function.
Traditionally, the tests look for specific mutations for a particular disease, while the condition could be caused by many different mutations that are passed from generation to generation.
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CEO of Professional Science Editing for Scientists @ prosciediting.com