Sentence examples for many mutants that from inspiring English sources

Many mutants that are dead or dying but not fully resorbed present deficits in cardiovascular function that can result from primary defects in heart function, blood differentiation or the vascular system.

In contrast to many mutants that lead to melanotic pseudotumors where it was difficult to decide whether melanization is due to changes in the affected tissue or in immune cells themselves, we are able to ascribe the response we observe to changes in the target (non-immune) tissue.

Many mutants that exhibit down-regulation of the Shh pathway show impaired Gli3 processing, with a decrease in the amount of Gli3 repressor relative to the amount of full-length Gli3 protein, as seen in mutants for Dync2h1/Dnchc2, IFT88/polaris, IFT172/wimple, Kif3a, Rpgrip1l/fantom and the chicken talpid mutant (38, 67– 69, 72, 73, 112).

P.K. et al.9 used γ-ray irradiation followed by immunoselection to obtain many mutants that no longer expressed one or more HLA specificities from the human lymphoblastoid cell line LCL 721.

Large-scale chemical mutagenesis screens in zebrafish led to the identification of many mutants that displayed widespread, apparently non-tissue-specific abnormalities [26], [27].

In the past few years cellular signaling pathways that interact with these hormonal pathways have yielded many mutants that extend lifespan in non-mammals.

Many PCP mutants that have disrupted convergent extension show decreased cochlear length.

Intriguingly, many PrP mutants that enter the ER lumen were found to be poorly degraded by ERAD, apparently relying instead on lysosomes (Ashok and Hegde, 2009).

On the other hand, the existence of many more mutants that seem to be intact in these surface structures but exhibit reduced biofilm phenotype showed that indeed various genes are required for the proper development of biofilm.

Many developmental mutants that affect the elaboration of the inflorescence have been isolated in maize [ 21] but, to date, only a few of the corresponding genes have been cloned.

Summarizing, sperm head shaping and nuclear condensation are tightly regulated processes involving proper chromatin remodelling and accurate assembly of cytoskeletal (manchette) and cytoplasmic (acrosome) structures as is demonstrated by the many mouse mutants that affect this process and hence fertility (Hermo et al., 2010; Kierszenbaum et al., 2007).