Exact(1)
Since the reduction in RNA that we observe is much greater than that, particularly for ΔTIn1m, pAm and ΔTpAm, we hypothesised that many mutant transcripts were being degraded, possibly as a result of impaired processing.
Similar(7)
In RNA from normal tissues from three families, mutant transcripts appeared unstable.
But it particularly preyed, as many mutant viruses do, on young adults.
Consistent with this, experimental manipulation of mef2ca mutant transcripts modifies the penetrance of the fate switch.
In the shoot of osnla1 mutant, transcripts of most of Pi transporters were induced (Fig. 3c).
Rab27a mutant mice (ashen mice), lack the Rab27a protein [21], as the mutant transcripts are nonfunctional [20].
Interestingly, the many mutants generated by those constructs were always attributable to the production of the fusion transcript, rather than an enhancer-like effect ([4] and unpublished data).
Extended Data Fig. 4 Reduction in mutant transcript levels is caused by mRNA decay.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com