Sentence examples for many mutant forms from inspiring English sources

This suggests that a single common dose and regimen of AT1001 may be sufficient to mediate a response of the enzyme in vivo for many mutant forms of α-Gal A. Fabry patients with responsive mutant forms of α-Gal A potentially are most likely to benefit from AT1001 treatment.

We can also hypothesise that the pro-apoptotic function is due to the action of one of the client proteins either stabilised under these conditions, such as mutant p53, or disengagement from one of its client proteins such as AKT/protein kinase B. Although it is known that HSP90 stabilises mutant p53 forms [ 94], many of these mutant forms contribute to cellular immortalisation and transformation.

Many mutant SOD1 proteins tend to become easily misfolded and form aggregates, especially under oxidative stress (3, 4).

These mutant forms hark back to Bosch's apocalyptic visions of disorder and self-destruction.

This "influential and controversial" group, reported the writer, "develop mutant forms of urbanism … which accept the megalopolitan condition with enthusiasm".

Histological analysis showed that we2 mutant forms abnormal endodermal cells.

Many mutant rice varieties with various phenotypes were generated after continuous selection and breeding.

Using traditionally crafty -- and often feminized -- media such as papier-mâché and yarn, Jackson renders mutant forms anything but comforting.

In contrast, cells expressing the Δ2A mutant formed as many colonies as the vector control cells, suggesting that the ability of LARP7 to assemble 7SK snRNP and suppress P-TEFb is necessary for its tumor suppressor potential.

While the E,E-SOD1S S form of all FALS mutants mE,E-SOD1S S37 °C, the E,E-SOD12SH form of mall mutants melts at or below 37 °C.

In order to determine how many mutants exist in a single nodule, we examined 22 nodules formed by the inoculation of two different pools of mutants.